KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EP300
All Species:
15.15
Human Site:
S1033
Identified Species:
27.78
UniProt:
Q09472
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q09472
NP_001420.2
2414
264161
S1033
E
E
D
Q
P
S
T
S
A
T
Q
S
S
P
A
Chimpanzee
Pan troglodytes
XP_515155
2411
263753
S1033
E
E
D
Q
P
S
T
S
A
T
Q
S
S
P
A
Rhesus Macaque
Macaca mulatta
XP_001102844
2414
264251
S1033
E
E
D
Q
P
S
T
S
A
T
Q
S
S
P
A
Dog
Lupus familis
XP_851777
2404
260682
G1034
E
E
E
N
S
A
N
G
A
T
S
Q
S
T
S
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
D1070
E
E
E
N
S
S
N
D
T
A
S
Q
S
T
S
Rat
Rattus norvegicus
XP_001076610
2413
263563
S1031
E
E
D
Q
P
S
T
S
A
A
Q
S
S
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233888
2444
267496
P1047
G
E
E
R
P
T
T
P
A
T
Q
S
S
P
A
Frog
Xenopus laevis
NP_001088637
2428
264402
N1060
E
E
E
N
G
G
A
N
S
S
L
Q
S
T
S
Zebra Danio
Brachydanio rerio
XP_001332718
2667
289125
A1042
E
E
E
G
S
E
S
A
T
S
Q
S
S
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
T1634
V
D
E
A
G
G
S
T
A
G
E
H
H
G
E
Honey Bee
Apis mellifera
XP_001122031
2606
284119
I1256
I
K
E
P
V
T
P
I
S
S
Q
D
T
T
D
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
L874
E
D
L
I
K
F
L
L
P
V
W
E
K
L
D
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
Q1279
K
D
G
A
M
S
T
Q
M
V
K
N
E
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
61
N.A.
58.6
94.1
N.A.
N.A.
85.1
60.4
57
N.A.
36.2
43
31.1
39.5
Protein Similarity:
100
99.7
99.5
72.4
N.A.
69.5
96.1
N.A.
N.A.
89.9
71
65.9
N.A.
46.6
54.9
45.6
51.5
P-Site Identity:
100
100
100
33.3
N.A.
26.6
93.3
N.A.
N.A.
66.6
20
33.3
N.A.
6.6
6.6
6.6
13.3
P-Site Similarity:
100
100
100
53.3
N.A.
40
93.3
N.A.
N.A.
86.6
53.3
66.6
N.A.
40
46.6
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
8
8
8
54
16
0
0
0
0
39
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
24
31
0
0
0
0
8
0
0
0
8
0
0
16
% D
% Glu:
70
70
54
0
0
8
0
0
0
0
8
8
8
0
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
8
16
16
0
8
0
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% H
% Ile:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
8
0
0
8
0
0
0
0
0
8
0
8
0
8
% K
% Leu:
0
0
8
0
0
0
8
8
0
0
8
0
0
8
0
% L
% Met:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
24
0
0
16
8
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
8
39
0
8
8
8
0
0
0
0
39
0
% P
% Gln:
0
0
0
31
0
0
0
8
0
0
54
24
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
24
47
16
31
16
24
16
47
70
8
31
% S
% Thr:
0
0
0
0
0
16
47
8
16
39
0
0
8
31
0
% T
% Val:
8
0
0
0
8
0
0
0
0
16
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _